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MONOPRIL

GENERIC MONOPRIL: Fosinopril

 

Fosinopril is a high blood pressure medication known as an ACE inhibitor. Angiotensin converting enzyme (ACE) is the enzyme in blood which controls the formation of angiotensin II, a chemical in blood that causes constriction of arteries and veins. Constriction of arteries and veins elevates blood pressure. Fosinopril is in a class of drugs called ACE inhibitors which inhibit ACE and block the formation of angiotensin II. By blocking the formation of angiotensin II, fosinopril relaxes the arteries and veins and lowers blood pressure. By reducing blood pressure, fosinopril also reduces the work that the heart must do to pump blood through the arteries and veins. This improves the output of blood from the heart. It is effective when used alone or in combination with other medications for the treatment of hypertension. Fosinopril is also prescribed for heart failure. This medication works by preventing the conversion of a chemical in your blood called angiotensin I into a more potent substance that increases salt and water retention in your body. Fosinopril also enhances blood flow in your circulatory system.

SIDE EFFECTS: Fosinopril is generally well tolerated. The most common side effects are headache, cough, dizziness, diarrhea, fatigue, nausea, vomiting, complaints of sexual dysfunction, and abnormal liver tests. Impairment of kidney function has been reported with ACE inhibitors, especially in patients with severe heart failure or kidney disease. In rare instances, low white blood cell counts have been reported with the use of captopril, another ACE inhibitor. (Low white blood cells increase a patient's risk of infections.).


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